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World Psoriasis Day Coming Up on October 29, 2009

Monday, October 26th, 2009

There is an estimated 125 million people affected by psoriasis living throughout the world.  Despite this fact, there is still a distinct lack of awareness about this condition among those who have it as well as those who don’t.

Thus psoriasis patients, medical specialists and other volunteers from around the world initiated the World Psoriasis Day.  This year, the event will occur on October 29th.  World Psoriasis Day exists to educate and empower people about psoriasis.

The International Federation of Psoriasis Associations will be the central organizer for World Psoriasis Day, as it has been from the beginning.  Throughout the year, members of this association meet and discuss the most pressing issues facing people with psoriasis today and then present these findings, including a variety of helpful resources, at this annual event.

Here are some of the most common misconceptions about psoriasis that WPD would like to dispel:

  • Psoriasis is contagious (it’s not).
  • There are no effective treatments for psoriasis (there are).
  • Psoriasis has to consume your everyday life (it doesn’t).

For more information about World Psoriasis Day see WorldPsoriasisDay2007.com (don’t mind the year listed in the URL).

Biological Psoriasis Meds an Example of Rising Health Care Costs

Friday, October 23rd, 2009

On my way to work today I heard a story on NPR’s Morning Edition about some deals that the Obama administration and Washington in general is trying to hammer out with major health companies, in particular with PhRMA (pronounced “pharma”), aimed at bringing down health care costs.

A woman with psoriatic arthritis was interviewed briefly to discuss the amazing, improving effect that biologics have had on her condition, all the while draining her health benefits dry every year, down to the last cent.  The name of the biologic she is taking wasn’t mentioned, but she said that each prescription refill costs about $2,000, which is expensive.  But, without it, she wouldn’t be able to walk.   I suspect that the biologic she is taking is Humira.

The point of the story was to juxtapose the amazing benefits of these new “wonder drugs” with the astronomical cost they incur for research and development.  Of course, this cost is eventually passed on to the patient (or the insurance company who picks up the tab).

Such extreme cost make these drugs harder to come by, especially for those with less than stellar health insurance.  In light of this dilemma the Obama administration and other forces in Washington have attempted to strike a deal with major drug companies that is supposed to bring down the cost of health care over the next 10 years by 2 trillion dollars.   I say “supposed to” because this depends on drug companies voluntarily not making as much profit as they otherwise could.  In return for their kindhearted generosity, the government will extend these companies’ exclusive rights to sell expensive biotech drugs (like the one mentioned above) by another 12 years.  This means that there won’t be any less expensive, generic versions of the drugs to compete, thus keeping the cost as high as possible for the next 12 years.

The problem here is that, if drug companies are smart enough to invent space-age biotech drugs, then they’re probably smart enough to do basic financial planning that would leave them coming out on top over the next 10-12 years.   One can only imagine how much they plan on making if they are willing to concede 2 trillion dollars.

Bleach Baths Found to Help with Eczema and Psoriasis Outbreaks

Monday, October 5th, 2009

Eczema is term that can be applied broadly to any kind of skin condition that results in flaky, irritated, itchy skin. Psoriasis has many of the same characteristics of this general condition, including cause (hereditary), symptoms (described above) and effective treatments (light therapy, for example).

The similarities between psoriasis and eczema inspired me to mention this new treatement that has been found to help people recover from severe eczema and/or psoriasis: Bleach baths.  You might ask your doctor if he/she thinks this would be worth a try.

Promising results for this treatment have been reported through a variety of news outlets and online forums (including here and here for example).

The prescribed concentration for these bleach baths is between a 1/4 and 1/8 cup bleach for a full bath.  This seems to kill any infection on the surface of the skin, thus allowing the body heal from the damaging effect of these skin conditions. Everyone I read about did not reporting smelling like bleach (or a swimming pool) and, in any case, it is recommended that the person soaking in the bath rinse off with regular water afterward.  Also, the consensus amongst people trying out this treatment is that soaking once or twice a day in bleach is needed to decrease outbreaks.

Incyte Announces Promising Results from New Topical Psoriasis Treatment Tests

Thursday, October 1st, 2009

Incyte has released some promising results regarding their new topical psoriasis treatment, INCB18424.  Patients with mild to moderate plaque psoriasis have reported up to 54% improvement after using this treatment.

INCB18424 is a cellular inhibitor, blocking some of the immune system’s functionality in particular.  Specifically it blocks JAK (Janus Kinase 1&2), which affect cytokine activity within the immune system.

Why is this a good thing?  The general consensus amongst the medical community is that psoriasis makes the immune system going haywire, which produces those notoriously psoriatic symptoms (scaly, itchy, irritated skin).  Thus, blocking some aspects of the body’s immune system will most likely block psoriasis flare ups.

INCB18424 is expected to have longer lasting effects and it should be more easily tolerated by a larger number of patients then the corticosteroids (a kind of steroid) and other topical treatments that are in everyday use right now for treating psoriasis.

INCB18424 has not yet been released for use by the general public.