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Psoriatic Arthritis

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What is Psoriatic Arthritis?

Sunday, December 6th, 2009

Psoriatic arthritis afflicts 10-30% of all patients who suffer with psoriasis and sets in much earlier than other forms of arthritis.  It appears approximately ten years after the first appearance of the condition. Treatment is similar to that of common osteoarthritis. Anti-inflammatory medications can be used to treat mild to moderate symptoms that include joint swelling and tendinitis.

Treatments for severe symptoms depend on the age and overall health of the patient. Injections of corticosteroids into the affected joints and immunosuppressants can help reduce discomfort.  There are five categories of psoriatic arthritis, some affect both sides of the body and others affect only one side. Research and discussions with your doctor will help you decide which treatments are best for you

Psoriatic Arthritis – Dealing With Joint Pain

Wednesday, November 25th, 2009

For most people, when you think of the word “arthritis” and the typical arthritis sufferer, you think of someone’s grandmother, with gnarled and knobby fingers, struggling to open a jar or hold a pen. The truth is that there are a number of different types of arthritis and they can hit people in the 20’s, 30’s, 40’s or even in childhood! One such type of arthritis is known as psoriatic arthritis. This particular form of inflammatory arthritis afflicts somewhere between 10 – 30% of those who suffer from the skin condition psoriasis. Typically appearing about 10 years after the first signs of psoriasis, psoriatic arthritis tends to afflict its sufferers much earlier in life than other forms of arthritis.

Arthritis is any one of a group of conditions that cause damage to the joints of the body. There are more than 100 different types of arthritis, with psoriatic arthritis being one of the more common forms. As with other types of arthritis, psoriatic arthritis is characterized by an inflammation of the joints. It can also be accompanied by tendinitis and severe swelling of the fingers and toes. For people that are suffering from this ailment, the swelling and tendinitis can cause just as much, if not more discomfort than the actual joint inflammation itself.

Treatment of psoriatic arthritis is similar to the treatment of basic osteoarthritis, and can include taking anti-inflammatory medications, such as naproxen. Other treatment options include the injection of specific corticosteroids into the affected joints or the prescription of certain immunosuppressants that can help reduce the body’s inflammatory response and therefore reduce the discomfort. The most severe cases are also being treated with special forms of DNA therapy, where different series of DNA that are not normally found together are combined, creating new, artificial DNA which can help prevent irreversible joint damage.

Psoriasis is estimated to affect somewhere between 2 and 3% of the western population of the world. It is a largely hereditary condition, and while treatable is not curable. Those that have psoriasis and then are later afflicted by psoriatic arthritis fall into one of five different categories of arthritis. Nearly half will have symmetrical arthritis and have joints on both sides impacted. The second most common form is asymmetrical, where only joints on one side of the body are affected. Regardless of what form you are struggling with, it is essential that you consult a physician at the first sign of arthritis, so that you will have the best array of treatment options available to you.

Biological Psoriasis Meds an Example of Rising Health Care Costs

Friday, October 23rd, 2009

On my way to work today I heard a story on NPR’s Morning Edition about some deals that the Obama administration and Washington in general is trying to hammer out with major health companies, in particular with PhRMA (pronounced “pharma”), aimed at bringing down health care costs.

A woman with psoriatic arthritis was interviewed briefly to discuss the amazing, improving effect that biologics have had on her condition, all the while draining her health benefits dry every year, down to the last cent.  The name of the biologic she is taking wasn’t mentioned, but she said that each prescription refill costs about $2,000, which is expensive.  But, without it, she wouldn’t be able to walk.   I suspect that the biologic she is taking is Humira.

The point of the story was to juxtapose the amazing benefits of these new “wonder drugs” with the astronomical cost they incur for research and development.  Of course, this cost is eventually passed on to the patient (or the insurance company who picks up the tab).

Such extreme cost make these drugs harder to come by, especially for those with less than stellar health insurance.  In light of this dilemma the Obama administration and other forces in Washington have attempted to strike a deal with major drug companies that is supposed to bring down the cost of health care over the next 10 years by 2 trillion dollars.   I say “supposed to” because this depends on drug companies voluntarily not making as much profit as they otherwise could.  In return for their kindhearted generosity, the government will extend these companies’ exclusive rights to sell expensive biotech drugs (like the one mentioned above) by another 12 years.  This means that there won’t be any less expensive, generic versions of the drugs to compete, thus keeping the cost as high as possible for the next 12 years.

The problem here is that, if drug companies are smart enough to invent space-age biotech drugs, then they’re probably smart enough to do basic financial planning that would leave them coming out on top over the next 10-12 years.   One can only imagine how much they plan on making if they are willing to concede 2 trillion dollars.

Genetic Testing by PsoriasisDX Offers Early Psoriatic Arthritis Detection

Thursday, October 1st, 2009

PsoriasisDX, a subsity of PharmaGenoma, has released a genetic testing kit that will help doctors to detect psoriatic arthritis. By detecting this condition early much irreversible joint damage can be prevented.

Cost for the kit: $399.00.

It involves taking a cheek swab test, which is then packaged up and sent to a PsoriasisDX laboratory for testing.  The lab then tests for an immune response gene variant called MICA-A9 (or MICA, for short).  Different independent studies have confirmed that subjects who have this gene variant tend to develop psoriatic arthritis (likelihood of 60%).

The logical question now would be: “Exactly how do I prevent psoriatic arthritis (or psoriasis in general)?”

Answer:  Keep reading this blog!

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Psoriatic arthritis affects about 20% of all people who have psoriasis.  It’s symptoms are similar in many ways to other forms of arthritis, though with a tendency to affect fewer joints and, of course, the fundamental cause is different.  Other symptoms include debilitating pain, swelling and joint deformation over longer periods of time.