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New Psoriasis Drug from Johnson and Johnson: Stelara (Ustekinumab)

Monday, September 28th, 2009

The National Institute for Health and Clinical Excellence (NICE) has approved Johnson and Johnson’s new psoriasis drug, Stelara, for use in the U.K.  The drug has also been approved for use in Canada but is still under review by the FDA.

It’s also expensive:  10,000 pounds, or about $16,000 USD per year.

Stelara works by targeting two specific proteins that play a major role in the body’s immune system: Interleukin 12 and Interleukin 23.  Regulating these proteins should reduce swelling and bring excessive skin cell production under control.

Administering this new drug should prove to be much more convenient than most other psoriasis treatments — it only needs to be taken 5 times a year via injection.  Thus far it has also proven to be safe.

In light of the unpredictable nature of psoriasis it is good to have as many treatment options, or as many avenues of attack, as possible.  In addition to developing resistance to certain treatments over time, psoriasis can also behave differently depending on the individual in question.  A treatment that works well for one individual might not work for another person and visa versa.

At this stage in the game Stelara is meant to treat moderate to severe plaque psoriasis (this is the most common type of psoriasis).  It is viewed as an option that should be tried only after other alternatives have proved to be ineffective.  This will most likely include a large percentage of the masses who currently suffer from psoriasis since so many are at their wits’ end trying to find an effective treatment for it.

Is Vitamin A an Effective Psoriasis Treatment?

Monday, September 28th, 2009

Vitamin A is believed by many to promote healthy skin in general.  As far as skin conditions go, it seems to be taken more commonly to treat acne.  Accutane is based on a derivative of Vitamin A.

Vitamin A helps your body resist psoriasis the same way that being healthy in general helps your body resist this condition.

Researchers tend to agree that psoriasis is related to misbehaving T-cells, thus, since vitamin A promotes healthy T-Cell activity, it may help to suppress psoriasis.  Vitamin A promotes effective body regeneration and discourages abnormal cell development.

It is possible to take too much vitamin A, so consult your doctor if you have any questions about what is right amount.  Consuming excessive amounts of vitamin A will cause it to store up in the body, eventually becoming toxic.

Vitamin A should be taken with other supplements since it needs the presence of other vitamins and minerals to work effectively.  In particular, be sure you are also taking it vitamin E, zinc and eating protein.

Side effects of taking too much vitamin A include hair loss, jaundice, nausea, blurred vision and decreased mental capacities.

Can Vitamin D Treat Psoriasis?

Monday, September 28th, 2009

Vitamin D is used around the world as one (of many) supplements that can treat psoriasis.  As an initial observation, this makes sense since Vitamin D is the nutrient that the body absorbs as a result of being out in the sun.

However, it should be noted that taking too much vitamin D (or derivatives thereof) can cause a variety of hazardous side effects, including hypercalcemia (too much calcium in the blood),  which causes nausea, disorientation, kidney failure, high blood pressure and coma.  Also, if you already have too much calcium coursing through your veins then vitamin D can increase your risk of developing kidney stones.  How much of a Vitamin D supplement is “enough’ (not too much) varies case by case, but the general consensus in the medical community is “less is more.”

Definitely consult your doctor before loading yourself up with vitamin D.

Calcipotriol (aka calcipotriene in the U.S.) is a derivative of vitamin D, which is administered as a topical treatment (cream) to treat psoriasis.  This drug has been proven to suppress excessive skin cell production and thus dramatically improve plaque psoriasis in particular.  It has also proven to be much safer than many other Vitamin D psoriasis treatments.  In the U.S. it is called “Dovonex” and is available by prescription only.

My New Psoriasis Product Idea: An Exfoliating Shampoo with Salicylic Acid

Saturday, September 26th, 2009

I thought of a brilliant idea for new psoriasis / flaky scalp shampoo: Something with salicylic acid (for psoriasis treatment) and also an exfoliating element to help remove dead skin / scales.

Then I googled it and found out that someone already thought of it.

Here it is, Optimum Care Dandruff Solutions Pre-Shampoo Exfoliating Treatment by Soft Sheen Carson
Optimum Care Dandruff Solutions Pre-Shampoo Exfoliating Treatment

Or, to be more specific, this is a “pre-shampoo product,” designed to clean-up / prep your scalp before applying regular shampoo.

I guess I’ll try to be faster next time creative-wise.  I’d still like to be able to sell a really big idea to a major drug company someday someday… then I’ll be set for a while.

This pre-shampoo by Soft Sheen Carson is designed for scalps suffering from itchiness or dandruff.  Some of the ingredients include salicylic acid and olive oil (new one for me).  Price: 5 bucks and change.